Bisphenol-A in dental composites 

General: 

Bisphenol A (BPA), already discovered in 1891, has been used since the 1950’s to harden polycarbonate plastics and resins, mainly used for the production of drinking bottles, eyeglass lenses, cell phones and eating utensils. Over the years studies have been conducted to determine possible health effects connected to the exposure of BPA. Opinions vary greatly. Some studies conclude that BPA poses no health risks while others state that BPA causes a number of adverse health effects.

Possible Hazard: 

In general, the European’s Scientific Committee on Emerging and Newly Identified Health Risks (SCENIHR), the European Chemicals Agency (ECHA), the European Food Safety Authority (EFSA), American Dental Association (ADA) and the US Food and Drug Administration (US-FDA) have concluded that current levels of BPA present no risk to the general population.

 

Although the scientific evidence at this time does not suggest that the very low levels (4 μg/kg b.w./day) of human exposure to BPA through the diet are unsafe, we have to keep a close eye on matters.

Dental Composites: 

BPA derivatives are used as main ingredient for the production of bisphenol A-glycidylmethacrylate (bis-GMA) which is the basic monomer for many dental composites. A recent article showed increased urinary BPA levels within 2 weeks after newly placed composite restorations. Fortunately, these concentrations are no longer detectable 6 month after placement. Another study among 160 composite resins from 31 manufacturers showed that > 85% of the composites in the market are based upon BPA derivatives. The small group using alternative monomers are not necessarily more biocompatible. The safety is not only related to the actual monomer but is more associated with the degree of polymerization. Therefore, additional studies for long-term effects on human health of all the different leaching monomers are still necessary. 

Quadrant Composite BPA – free!: 

As Cavex takes the risk of BPA very serious, we only use a very high and pure grade bis-GMA in our production, minimizing the amount of bisphenol A. Also additional testing on the leached monomers from composite filling has been performed. Based upon our knowledge and findings of the studies, we can state that our Quadrant composites and bonding are BPA-free and can be used safely. 

Haarlem, 28 November 2016
Cavex Holland B.V. 
Manager Technical Services 
Richard Woortman 

 

Reference: 

SCENIHR 02-2015 
Final opinion on the safety of the use of bisphenol A in medical devices

ECHA 12-2015 
Committees finalize evaluation of bisphenol A restriction proposal

EFSA 2015 
Scientific opinion on bisphenol A

EFSA 10-2016 
New immune system evidence useful but limited

ADA 2014 
Statement on bisphenol A and dental materials

ADA 2016
Bisphenol A released from resin based dental sealants

FDA 2015 
Current perspective on BPA in food contact applications

J.Am Dent Assoc. 2016.
Changes in Urinary bisphenol A concentrations associated with placement of dental composite restorations in children and adolescents

The Open Dentistry Journal 2016.
Bisphenol A Release: Survey of the Composition of Dental Composite Resins

 

 
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